Journal of thrombosis and haemostasis : JTH
Combined Immunohistochemical and Proteomic Description of Neutrophil Extracellular Trap (NET) Burden in Acute Ischemic Stroke Thrombi.
Eric Sleasman, Sajal Medha Akkipeddi, Siddharth Chittaranjan, Kiernan Gunn, Lexi Thomson, Prasanth Romiyo, Derek George, Tarun Bhalla, Thomas K Mattingly, Kevin Welle, Sina Ghaemmaghami, Mary Wines-Samuelson, Linda Callahan, Kimberly Martinod, Craig Morrell
Published: 202610.1016/j.jtha.2025.12.027
Abstract
BACKGROUND: Neutrophil extracellular traps (NETs) are important in host defense but implicated in pathological thrombosis in acute ischemic stroke (AIS). NET quantification is typically done with immunostaining for NET-specific markers, but molecular…
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