Journal of thrombosis and haemostasis : JTH
Laminin G domains define a critical interface for protein S-mediated factor IXa inhibition.
Rafika Yasmin, Rima Chattopadhyay, Vandana, Narender Kumar, Adrianne Dorsey, Sabyasachi Chatterjee, Sumita Choudhury, Vijaya Satish Pilli, Brenda Temple, Rinku Majumder
Published: 202610.1016/j.jtha.2025.11.035
Abstract
BACKGROUND: Hemostasis is maintained through a delicate balance between procoagulant and anticoagulant mechanisms. Protein S (PS), a multidomain, vitamin K-dependent glycoprotein, contributes to this balance not only as a cofactor for activated prote…
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