Journal of thrombosis and haemostasis : JTH
Optimal adherence thresholds for oral anticoagulants in patients with atrial fibrillation using machine learning and population administrative data.
Abdollah Safari, Hamed Helisaz, Mina Tadrous, Marc W Deyell, Jason G Andrade, Shahrzad Salmasi, Adenike Adelakun, Kristian B Filion, Mary A De Vera, Peter Loewen
Published: 202510.1016/j.jtha.2025.10.031
Abstract
BACKGROUND: Adherence to oral anticoagulants (OACs) for atrial fibrillation (AF) stroke prevention is traditionally defined as taking 80% of doses as prescribed, but this threshold has not been clinically validated. OBJECTIVES: We identified OAC adhe…
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