Journal of thrombosis and haemostasis : JTH
Successful use of recombinant ADAMTS13 in a pregnant patient with immune-mediated thrombotic thrombocytopenic purpura.
Raphael Cauchois, Pascale Poullin, Alexandre Hertig, Bérangère Joly, Gilles Kaplanski, Paul Coppo
Published: 202510.1016/j.jtha.2025.10.012
Abstract
We report the first case of immune-mediated thrombotic thrombocytopenic purpura (iTTP) successfully treated with recombinant ADAMTS13 (rhADAMTS13) during pregnancy. A 36-year-old woman with a history of severe iTTP and persistently undetectable ADAMT…
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