Journal of thrombosis and haemostasis : JTH
Unraveling the molecular mechanism of in situ surface-initiated thrombogenesis.
Adam Hansen, Georgios Kementzidis, Bernard Essuman, Ziyuan Niu, Jawaad Sheriff, Volodymyr Chernyshenko, Yuefan Deng, Miriam Rafailovich, Dennis K Galanakis
Published: 202510.1016/j.jtha.2025.09.042
Abstract
BACKGROUND: Thrombosis caused by contact of blood with surfaces is a serious complication in the incorporation of biomedical devices. Adsorption of fibrinogen to these commonly hydrophobic surfaces can lead to conformational changes in the molecule,…
Preview only. Read the full abstract at the source