Journal of thrombosis and haemostasis : JTH
Reduced vs full-dose direct oral anticoagulants for extended treatment of cancer-associated venous thromboembolism: a systematic review and meta-analysis of randomized trials.
Larissa A de Lucena, Amanda G Duarte, Larissa C Hespanhol, Juliana Muniz, Nicole Félix, Kleyton Medeiros, C Michael Gibson
Published: 202510.1016/j.jtha.2025.09.026
Abstract
BACKGROUND: Patients with cancer-associated venous thromboembolism (VTE) are at high risk of recurrent thrombosis and bleeding during prolonged anticoagulation. While full-dose direct oral anticoagulants (DOACs) are widely used, the safety and effica…
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