Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS)ZincRatsAnimalsCell SurvivalCalcium Channels
Zn2 + alleviates ischemia/reperfusion injury in H9c2 cells by modulating mitochondrial biogenesis and dynamics via MCU.
Bingyu Wang, Bohan Xing, Luyao Huang, Xiaoyi Li, Xiyun Bian, Jinkun Xi
Published: 202510.1016/j.jtemb.2025.127769
Abstract
BACKGROUND: Zinc is an essential nutrient implicated in cardiovascular health. This study investigates whether Zn2+ protects H9c2 cells by regulating mitochondrial biogenesis, dynamics, and calcium homeostasis via the mitochondrial calcium uniporter…
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