The Journal of thoracic and cardiovascular surgery
Integrin αV emerges as a potential therapeutic target with cautionary implications in thoracic aortic aneurysm and dissection.
Sheng-An Su, Yuan Zhu, Zhanzeng Feng, Zhanglong Hu, Jixie Le, Chao Chen, Jian Shen, Shiyu Zhu, Shuang Wu, Hong Ma, Meixiang Xiang, Yao Xie
Published: 202510.1016/j.jtcvs.2025.10.006
Abstract
OBJECTIVE: Thoracic aortic aneurysm (TAA) is a life-threatening condition that predisposes to aortic dissection (AD), yet its underlying pathophysiologic mechanisms remain poorly understood. METHODS: Tandem mass tag-based quantitative proteomics of p…
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