Transplantation and cellular therapy
Acute Myeloid Leukemia Patients With Myelodysplasia-Related Gene Mutations Benefit From Post-Transplant Hypomethylating Agent Maintenance.
Jiayu Huang, Yi Xia, Mengqi Xiang, Ran Zhang, Yang Yang, Hongru Chen, Changwei Dong, Su Li, Jun Zhu, Chengwei Jin, Luxiang Wang, Chuanhe Jiang, Wenxuan Huo, Zengkai Pan, Yilei Ma
Published: 202510.1016/j.jtct.2025.12.951
Abstract
Relapse remains the major cause of mortality in adverse-risk acute myeloid leukemia (AML) patients receiving allogeneic hematopoietic stem cell transplantation (allo-HSCT). Hypomethylating agent (HMA) maintenance is a strategy to prevent post-transpl…
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