Journal of theoretical biology
Simple cellular Potts model of scratch assays on healthy and keloid fibroblasts driven by contact inhibition of locomotion.
Stéphane Urcun, Yasmin El Mahi, Raluca Eftimie, Zélie Dirand, Gwenaël Rolin, Stéphane P A Bordas
Published: 202610.1016/j.jtbi.2025.112365
Abstract
In this study, we propose and validate a simple agent-based model to study cell-cell interactions and cell migration during in vitro scratch assays in the context of cutaneous fibrosis (keloid). For model parametrization, we collect data from in vitr…
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