Journal of theoretical biologyPolymorphismSingle NucleotideVirus InternalizationNiemann-Pick C1 ProteinHumans
Evaluating the impact of NPC1 single nucleotide polymorphisms on entry efficiency of filoviruses in vitro: Agent-based model approach.
Juseong Kim, Kwang Su Kim, Ayato Takada, Yusuke Asai, Shingo Iwami, Seung-Woo Son, Mi Jin Lee
Published: 202610.1016/j.jtbi.2025.112315
Abstract
Ebola and Marburg viruses are highly pathogenic filoviruses that cause severe hemorrhagic fever in humans, with case fatality rates reaching approximately 50 %. These viruses pose significant public health challenges owing to their potential for larg…
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