Journal of stroke and cerebrovascular diseases : the official journal of National Stroke AssociationAnimalsEndoplasmic Reticulum StressMaleCerebral HemorrhageSignal Transduction
Knockdown of programmed cell death 4 inhibits endoplasmic reticulum stress in male mice with intracerebral hemorrhage through the phosphoinositide 3-kinase/protein kinase B pathway.
Jianfeng Qi, Zhimin Zhang, Jixiang Yin, Xuhui Yuan, Xu Wang, Zexiang Liu, Yuhang Liu, Jianjun Wang
Published: 202610.1016/j.jstrokecerebrovasdis.2026.108554
Abstract
BACKGROUND: Pdcd4 is a potential target for intracerebral hemorrhage (ICH) treatment. This research intended to elucidate the mechanism by which Pdcd4 regulates ICH progression. METHODS: Male mice were infected with sh-Pdcd4 lentivirus, followed by i…
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