The Journal of surgical research
Resveratrol Suppresses Sepsis-Induced Micro-vascular Hypo-Reactivity Through Rac1-MLCK Pathway.
Yang Yang, Jun-Chao Liu, Zhen-Kui Liu, Yu-Ping Zhang, Min Xi, Hai-Ning Zheng, Jing Wang, Zhen-Ao Zhao, Chun-Yu Niu, Zi-Gang Zhao
Published: 202610.1016/j.jss.2025.12.021
Abstract
INTRODUCTION: Vascular hyporeactivity contributes to a high mortality rate in sepsis. Resveratrol (Res) exhibits anti-inflammatory properties and improves vascular reactivity in septic animals. However, the mechanism of action of Res in sepsis-induce…
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