The Journal of surgical research
Impact of Pirfenidone Administration Routes on Colon Anastomosis and Healing in Rats.
Ali Duran, Ferhat Çay, Nelin Hacıoğlu, Esra Tokay, Feray Köçkar, Eren Altun, Azad Gazi Şahin, Hüseyin Pülat, Alev Çetin Duran
Published: 202510.1016/j.jss.2025.11.050
Abstract
INTRODUCTION: Anastomotic strictures are a prevalent complication in colorectal surgery. This study aimed to investigate the antifibrotic effects of pirfenidone on colorectal anastomotic stenosis, abdominal wall wound healing, and adhesion formation…
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