The Journal of surgical researchAnimalsSepsisMiceKnockoutApoptosis
Ppif Gene Knockout Alleviates Pancreatic Injury in Mice With Cecal Ligation and Puncture-induced Sepsis.
Lijie Ma, Junjie Wang, Sheng Wang
Published: 202510.1016/j.jss.2025.10.020
Abstract
INTRODUCTION: The peptidyl-propyl cis-trans isomerase F (Ppif) gene encodes cyclophilin D. Its involvement suggests that sepsis-induced pancreatic injury may relate to mitochondrial membrane pore transition proteins, offering potential targets for pa…
Preview only. Read the full abstract at the source