The Journal of steroid biochemistry and molecular biologyHumansTriple Negative Breast NeoplasmsTamoxifenFemaleSignal Transduction
Increased TGF-β signaling during antiestrogen therapy in triple-negative breast cancer cells.
Nandani Dharwal, Deepshikha Rathore, Nirali Shukla, Heena V Dave
Published: 202610.1016/j.jsbmb.2025.106934
Abstract
Antiestrogen therapies, such as Tamoxifen (TAM), are widely used in managing estrogen receptor-positive (ER+) breast cancer (BC); however, resistance to these agents remains a significant clinical challenge. Triple-negative breast cancer (TNBC) repre…
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