The Journal of steroid biochemistry and molecular biologyHumansHexosaminesBreast NeoplasmsFemaleDisease Progression
The hexosamine biosynthesis pathway as a potent culprit in breast cancer progression.
Maryam Musavi, Farnaz Oghbaei, Mohammad Abavisani, Ahmad Ghasemi, Amir Abbas Momtazi-Borojeni
Published: 202610.1016/j.jsbmb.2025.106932
Abstract
The hexosamine biosynthesis pathway (HBP) is a nutrient-sensitive branch of glucose metabolism that produces UDP-GlcNAc, a central substrate for protein glycosylation. Growing evidence links altered HBP activity to breast cancer (BC) progression and…
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