The Journal of steroid biochemistry and molecular biologyAnimalsAldosteroneMaleRatsHypertension
Esaxerenone attenuates high salt-induced hypertension and renal damage via CD8+T cell- associated NCC activation in aldosterone treated rats.
Chang Xu, Nan Zhai, Hongshuang Wang, Fang Fang, Jingwen An, Fengrui Liu, Yan Zhong, Zheng Wang, Xiangting Wang
Published: 202610.1016/j.jsbmb.2025.106884
Abstract
Salt-water retention plays key roles in chronic kidney disease (CKD) and hypertension. The mineralocorticoid receptor (MR) blocker esaxerenone could attenuate hypertension and renal injury; however, the mechanism is only partially understood. In this…
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