Journal of psychiatric researchAnimalsHippocampusMiceOxidative StressSeizures
Cuminaldehyde improves seizures by reducing the expression of TNF-α, iNOS, nNOS, and oxidative stress in the hippocampus.
Najmeh Asgharzadeh, Parsa Eshragh, Hossein Amini-Khoei, Nahid Jivad, Amir Ali Khavasi, Marzieh Mardani, Hasan Ali Abedi, Elham Bijad, Diana Shahrani Korrani, Mohammad Shahrani Korrani, Mehrdad Shahrani Korrani
Published: 202610.1016/j.jpsychires.2025.10.023
Abstract
INTRODUCTION AND OBJECTIVE: Neuroinflammation is a significant contributor to seizure occurrence. This study examines the anticonvulsant effects of cuminaldehyde. MATERIALS AND METHODS: Forty-eight NMRI mice weighing 25-30 grams and 2 months old were…
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