Journal of proteomicsHumansCopperBreast NeoplasmsProteomeFemale
Dinuclear Cu2+-complexes disrupt cellular pathways and rewire the breast cancer proteome.
Zeinab Ghasemishahrestani, Simone Santiago Carvalho de Oliveira, Rafaela Dos Santos Moraes Francisco, Luis Felipe Costa Ramos, Renata Maria Dos Santos, Gilberto Barbosa Domont, Nicolás A Rey, André Luis Souza Dos Santos, Fabio Cesar Sousa Nogueira, Marcos Dias Pereira
Published: 202610.1016/j.jprot.2025.105570
Abstract
Cancer's global burden highlights the urgent need for more effective therapies. Metal-based drugs, particularly Cu2-complexes, offer promising alternatives due to copper's diverse biological functions. This study investigates the antitumor potential…
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