Journal of pharmacological sciencesrho-Associated KinasesHumansEpithelial-Mesenchymal TransitionMaleCell Proliferation
Rho kinase 2 promotes epithelial-mesenchymal transition and proliferation in human prostate cancer PC-3 cells.
Alamgir Hossain, Aya Yamamura, Md Junayed Nayeem, Sivasundaram Karnan, Rie Takahashi, Hisaki Hayashi, Motohiko Sato
Published: 202510.1016/j.jphs.2025.09.007
Abstract
Prostate cancer is the second most common cancer in men. Although androgen deprivation therapy is initially effective, resistance inevitably develops. Most patients eventually progress to castration-resistant prostate cancer, a stage with limited tre…
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