The Journal of pharmacology and experimental therapeutics
Enhancing local glioblastoma treatment via in vitro synergistic pairing of Janus kinase/signal transducer and activator of transcription-3 inhibitor with antiepileptic drugs.
Alexandra-Iulia Bărăian, Lajos Raduly, Oana Zănoagă, Bogdan-Cezar Iacob, Ioana Berindan-Neagoe, Ede Bodoki
Published: 202510.1016/j.jpet.2025.103767
Abstract
The heterogeneity and treatment resistance of glioblastoma (GBM) can be addressed through multidrug combination therapies that target multiple biological pathways simultaneously. In this study, we explored the repurposing of antiepileptic drugs with…
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