The Journal of pharmacology and experimental therapeuticsAnimalsFentanylSwineAntibodiesMonoclonal
An antifentanyl monoclonal antibody reverses fentanyl-induced apnea in pigs.
Carly Baehr, Eduardo Hatschbach, Jennifer Vigliaturo, Dustin Hicks, Sujata Pandit, Marcellene Hollingsworth, Heather Green, Derrick Hau, Elaine Gay, Ann M Decker, Brooke Hoppe, Aaron Khaimraj, David Aucoin, Scott P Runyon, Alonso G P Guedes
Published: 202510.1016/j.jpet.2025.103743
Abstract
The incidence of fatal drug overdoses has increased dramatically over the past decade due to the widespread availability of fentanyl and its analogs. As a complementary strategy to current overdose reversal agents, monoclonal antibodies (mAbs) are in…
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