Journal of pediatric surgery
Prenatal administration of Immunoglobulin-M (IgM) via transamniotic fetal immunotherapy (TRAFIT).
Alex L Huang, Emily M Scire, Tanya T Dang, Melody Tai, Beatriz S Bechara, Blen Yohannes, Ina Kycia, David Zurakowski, Dario O Fauza
Published: 202510.1016/j.jpedsurg.2025.162901
Abstract
PURPOSE: Immunoglobulin-M (IgM) is the first antibody class produced during an immune response, playing a crucial role in early defense mechanisms. Its large pentameric or hexameric structure, however, prevents it from crossing the placenta from moth…
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