Journal of pharmaceutical and biomedical analysisAnimalsTandem Mass SpectrometryImmunoglobulin GChromatographyHigh Pressure Liquid
Importance in optimization of sample volume in the IgG-immunoaffinity UPLC-MS/MS assay for quantification of a therapeutic antibody in monkey serum.
Kenji Kita, Yuji Mano
Published: 202610.1016/j.jpba.2026.117334
Abstract
E6011 is a novel monoclonal antibody developed for the treatment of rheumatoid arthritis. Ultra-performance liquid chromatography coupled with tandem mass spectrometry (UPLC-MS/MS) has become increasingly important in the assays of therapeutic antibo…
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