Journal of integrative medicine
Protective effects of Prunella vulgaris polysaccharides against herpes simplex virus type 1 infection through the STING-TBK1-IRF3 pathway.
Yi-Bo Zhang, Lin Xu, Man Yuan, Meng-Fan Liu, Yang Li, Xuan-Lei Zhong, Zhi-Xiu Lin, Yan-Fang Xian, Ping Lu, Zhi-Chao Xi, Hong-Xi Xu
Published: 202510.1016/j.joim.2025.12.008
Abstract
OBJECTIVE: Enhancing innate immunity through interferons (IFNs) and IFN-stimulated genes (ISGs) offers a promising strategy for preventing herpes simplex virus type 1 (HSV-1) infection. Prunella vulgaris L., a medicinal herb, has demonstrated signifi…
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