Osteoarthritis and cartilageAnimalsMiceArthritisExperimentalOsteoarthritis
Loss of peptidergic innervation of the subchondral bone in a murine model of MIA-induced osteoarthritis.
Jason Ivanusic, Wendy Imlach, Jenny Thai, Jacob Bos, Jackson Hart, John-Paul Fuller-Jackson
Published: 202510.1016/j.joca.2025.09.016
Abstract
OBJECTIVE: In the present study, we aimed to determine how osteoarthritis (OA) affects the morphology and distribution of nociceptive nerve endings in the subchondral bone of animals with mono-iodoacetate (MIA)-induced OA. DESIGN: We used a modified…
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