Journal of neuroimmunologyAnimalsFreund's AdjuvantMiceEncephalomyelitisAutoimmune
Early exposure of NOD/ShiLtJ mice to Freund's adjuvant prompts delayed, spontaneous progressive encephalomyelitis.
Giuseppe Ranieri, Alberto Chiarugi, Daniela Buonvicino
Published: 202610.1016/j.jneuroim.2025.578809
Abstract
Drugs able to efficiently counteract primary progressive MS (PP-MS) remain an unmet need. The availability of reliable animal models of PP-MS might boost the identification of treatments capable of counteracting disease evolution. Recently, we charac…
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