Acupuncture mitigates sciatic neuropathic pain in lumbar disc herniation via inhibiting spinal CXCL12/CXCR4-driven glial activation and neuroinflammation.

Lumbar disc herniation (LDH) is a prevalent degenerative spinal disorder causing chronic low back pain and sciatica through persistent neuroinflammation and central sensitization. Increasing evidence implicates the CXCL12/CXCR4 signaling axis in thes…

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