Journal of neuroscience methodsAnimalsMiceRose BengalSkullDisease Models
Long term direct visualization of the photothrombotic cortical infarction through the intact skull of anesthetized mice.
Juliette Leclerc, Théotime Briar, Caroline Derouck, Cheima Mortier, Célia Duclos, Karelle Bénardais, Eric Verin, Jean-Paul Marie, Julien Chuquet
Published: 202610.1016/j.jneumeth.2026.110683
Abstract
BACKGROUND: To assess post-stroke functional recovery and develop new treatments, numerous preclinical models have been developed, including the photothrombotic stroke model. This reproducible and simple method induces a targeted ischemic lesion in a…
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