The Journal of molecular diagnostics : JMD
Dideoxy Sequencing Enhances Detection of KIT Mutations in Gastrointestinal Stromal Tumors Initially Evaluated by Next-Generation Sequencing Hotspot Panels.
Lisa Robinson, Sharleen Rapp, Weiwei Zhang, Jaclyn Pope, Allison M Cushman-Vokoun
Published: 202510.1016/j.jmoldx.2025.11.005
Abstract
Gastrointestinal stromal tumors (GISTs) are predominantly characterized by mutations in KIT or PDGFRA. Mutation detection is important for optimal therapy. Next-generation sequencing (NGS) panels are useful in GIST assessment as they allow for simult…
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