Journal of molecular graphics & modelling
Computational modeling of ubiquitin specific protease 7 (USP7) complexes with N-benzylpiperidinol derivatives incorporating binding site flexibility.
Jorge Luis Valdés-Albuernes, Erbio Díaz-Pico, José Luis Velázquez-Libera, Julio Caballero
Published: 202610.1016/j.jmgm.2025.109272
Abstract
Ubiquitin-specific protease 7 (USP7) is a key regulator of protein homeostasis, playing critical roles in various cellular processes, including DNA damage response, immune signaling, and oncogenesis. Targeting USP7 with small-molecule inhibitors has…
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