Journal of molecular graphics & modellingReceptorFibroblast Growth FactorType 1Molecular Dynamics SimulationDrug Design
In silico approaches for the identification of novel FGFR1 inhibitor in cancer: A fragment-based De novo drug designing guided virtual screening approach.
Nidhi Bala, Ashwini Pareek, Agnidipta Das, Bharti Devi, Vinod Kumar, Vikas Jaitak
Published: 202610.1016/j.jmgm.2025.109207
Abstract
The fibroblast growth factor receptor 1 (FGFR1) plays a crucial role in cancer development and progression, primarily through mechanisms involving carcinogenesis and angiogenesis. Aberrant FGFR1 signalling has been implicated in various cancers, incl…
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