Journal of molecular biology
AggrescanAI: Prediction of Aggregation-Prone Regions Using Contextualized Embeddings.
Alvaro M Navarro, Santiago Palacios, Thierry Galmarini, Oriol Bárcenas, Salvador Ventura, Cristina Marino-Buslje
Published: 202610.1016/j.jmb.2026.169643
Abstract
Protein aggregation plays a central role in the pathogenesis of many neurodegenerative diseases and poses major challenges in protein engineering. A key driver of this process is the presence of aggregation-prone regions (APRs) within protein sequenc…
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