Journal of molecular biologyEscherichia coliExodeoxyribonuclease VEscherichia coli ProteinsProtein BindingBase Pairing
The Nuclease Domain of E. coli RecBCD Helicase Regulates DNA Binding and Base Pair Melting.
Linxuan Hao, Rui Zhang, Timothy M Lohman
Published: 202610.1016/j.jmb.2025.169571
Abstract
E. coli RecBCD, a hetero-trimeric helicase and nuclease, functions in double stranded (ds) DNA break repair. RecBCD possesses ATPase motor domains within both RecB (3'-5') and RecD (5'-3') and a nuclease domain within RecB (RecBNuc). RecBCD binds to…
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