Journal of molecular biologyCRISPR-Cas SystemsRNACRISPR-Associated ProteinsProtein DomainsGene Editing
Synthetic Type III-E CRISPR-Cas Effectors for Programmable RNA-targeting.
Daniel J Brogan, Calvin P Lin, Elena Dalla Benetta, Tianqi Wang, Fangying Chen, Harry Li, Claire Lin, Elizabeth A Komives, Omar S Akbari
Published: 202610.1016/j.jmb.2025.169566
Abstract
The recent discovery of the type III-E class of CRISPR-Cas effectors has reshaped our fundamental understanding of CRISPR-Cas evolution and classification. Type III-E effectors are composed of several Cas7-like domains and a single Cas11-like domain…
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