Journal of molecular biologyHumansTumor MicroenvironmentTranscriptomeBreast NeoplasmsGene Expression Profiling
SpatialFusion: A Unified Model for Integrating Spatial Transcriptomics to Unveil Cell-type Distribution, Interaction, and Functional Heterogeneity in Tissue Microenvironments.
Mengqiu Wang, Zhiwei Zhang, Xinxin Zhang, Ruoyan Dai, Zhenghui Wang, Zeyao Chen, Lixin Lei, Zhenxing Li, Qianjin Guo
Published: 202610.1016/j.jmb.2025.169535
Abstract
Recent advances in spatial transcriptomics (ST) have significantly enhanced our understanding of tissue structure and intercellular interactions. However, existing methods for spatial domain identification and cell type deconvolution still face chall…
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