Journal of molecular biologyPeptide SynthasesBinding SitesProtein DomainsProtein BindingModels
Slow Dynamics Orchestrate Communication Between Binding Sites in the Condensation Domain of a Non-ribosomal Peptide Synthetase.
Megha N Karanth, Debajyoti De, John P Kirkpatrick, Mark Jeeves, Teresa Carlomagno
Published: 202510.1016/j.jmb.2025.169484
Abstract
Non-ribosomal peptide synthetases (NRPSs) are complex molecular machineries that synthesize non-proteinaceous peptides in microorganisms. These peptides (NRPs) usually present a wide range of biological activities and are highly regarded as potential…
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