Synthesis and lanthanum coordination of a BzMacropa analogue for convenient solid-phase peptide synthesis towards targeted alpha therapeutic discovery.

The alpha-emitting isotope actinium-225 is a promising radiometal for developing targeted alpha therapeutics (TAT) to treat malignant diseases. Actinium-225 has a half-life of 9.92 days and a decay chain emitting four alpha-particles. Alpha particle…

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