Journal of inorganic biochemistryIridiumPhenothiazinesSinglet OxygenPhotochemotherapyHumans
Exploring the singlet oxygen generation of iridium(III) complex containing phenothiazine for photodynamic therapy.
Qinglin Chen, Hong Zeng, Jie Wu, Yuanyan Li, Yibao Li, Yongquan Wu
Published: 202610.1016/j.jinorgbio.2025.113149
Abstract
As a photochemical-based treatment approach, photodynamic therapy (PDT) relies on a photosensitiser (PS) that produces reactive oxygen species (ROS) after irradiation, which lead to irreparable cell damage and hence cell death. Cyclometalated iridium…
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