Journal of inorganic biochemistryTrypanosoma cruziThiosemicarbazonesHumansTrypanocidal AgentsLigands
Novel cationic gold(I) compounds with 5-nitrofuryl containing thiosemicarbazone ligands exhibit activity against Trypanosoma cruzi.
Carla Albornoz, José Ortega-Campos, Germán Barriga-González, Juan Diego Maya, Dinorah Gambino, Lucía Otero, Pablo Fuentealba, Claudio Olea Azar, Esteban Rodríguez-Arce
Published: 202610.1016/j.jinorgbio.2025.113131
Abstract
Searching for more effective chemotherapeutic agents for the treatment of American Trypanosomiasis, a disease caused by the parasite Trypanosoma cruzi (T. cruzi), the development of gold(I) compounds represents a promising strategy. In this work, fou…
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