Journal of inorganic biochemistry
Exploring a novel asymmetric tris-heteroleptic iridium(III) complex as mitochondria-targeted anticancer agents.
An-Li Liu, Si-Yu Chen, Qin Zhou, Fa-Biao Yu, Gao-Nan Li, Zhi-Gang Niu
Published: 202510.1016/j.jinorgbio.2025.113102
Abstract
Organometallic iridium(III) complexes are a highly promising class of metal-based anticancer agents. In this study, three bis-/tris-heteroleptic iridium(III) complexes-[Ir(piq)2(bpy)]PF6 (Ir1), [Ir(piq)(btp)(bpy)]PF6 (Ir2) and [Ir(btp)2(bpy)]PF6 (Ir3…
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