Journal of immunological methodsAnimalsApoptosisOligodeoxyribonucleotidesStreptococcus thermophilusCaspase 8
CpG-ODN from Streptococcus thermophilus as a tool for inducing extrinsic apoptosis via caspase-8 activation in mouse splenocytes.
Md Rayhan Chowdhury, Takuma Okajima, Aito Murakami, Ariful Islam, Takeshi Shimosato
Published: 202510.1016/j.jim.2025.113999
Abstract
Synthetic oligodeoxynucleotides (ODNs) containing unmethylated CpG motifs activate Toll-like receptor 9 (TLR9), thereby triggering a diverse range of immunomodulatory responses. Although the immune-stimulating properties of CpG-ODNs have been extensi…
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