The Journal of investigative dermatology
The Role of Mast Cells in the Pathophysiology of Chronic Prurigo.
Manuel P Pereira, Monique Butze, Carolina Vera Ayala, Pavel Kolkhir, Martin Metz
Published: 202510.1016/j.jid.2025.09.365
Abstract
Chronic prurigo (CPG) is a highly itchy skin condition with unclear pathophysiology. The promising therapeutic effects of the tyrosine kinase KIT antibody barzolvolimab in an early-stage clinical trial have highlighted the crucial role of mast cells…
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