The Journal of investigative dermatology
The Role of MRGPRX1 in the Melanogenesis of Human Primary Epidermal Melanocytes.
Sae Woong Oh, Eunbi Yu, Kitae Kwon, Gyeonghyeon Kim, Hee Seon Shin, Seokhyeon Min, Yeonsoo Kim, Ki Wook Lee, Minkyung Song, Jae Youl Cho, Jongsung Lee
Published: 202510.1016/j.jid.2025.09.016
Abstract
MRGPRX1 (mas-related G protein-coupled receptor X1) is an orphan receptor, and its function in the skin cells remains unclear. In this study, we demonstrated MRGPRX1 expression in skin cells, including melanocytes. We also found that MRGPRX1 knockdow…
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