Journal of hepatology
MARCO+ macrophages drive immunosuppressive remodeling and metastasis in chemotherapy-associated steatohepatitis.
Ke Ding, Anrong Mao, Yong Wang, Zhu Ni, Yuze Shi, Kanghui Liu, Jingyao Zhang, Weiting Zheng, Lei Liu, Qiaoyu Liu, Yijin Huang, Qingxiang Xu, Shiyu Wang, Beicheng Sun, Wenjie Zhang
Published: 202510.1016/j.jhep.2025.11.008
Abstract
BACKGROUND & AIMS: Chemotherapy-associated steatohepatitis (CASH) is a common side effect of patients with colorectal liver metastases (CRLM) treatment that may affect patient outcomes. However, the mechanisms remain poorly understood. METHODS: CD45+…
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