Journal of hazardous materials
Perfluorooctane sulfonates drives colitis via a gut microbiota-bile acid-endoplasmic reticulum stress axis in mice: Mechanistic validation and targeted interventions.
Huanjuan Yan, Changxiong Wang, Haoran Wang, Jian Liu, Hongfei Zhou, Wenxuan Zhong, Xiaodong Wang, Yongping Chen, Zhiran Ju, Haibin Tong, Ya Zhang
Published: 202610.1016/j.jhazmat.2026.141122
Abstract
Perfluorooctane sulfonate (PFOS), a widespread environmental pollutant, is implicated in systemic toxicity, yet its role in colitis remains unclear. This study aimed to investigate whether PFOS exacerbates colitis via the gut microbiota-bile acid-end…
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