Journal of hazardous materialsAtherosclerosisAnimalsFluorocarbonsAlkanesulfonic AcidsHyperplasia
Perfluorooctane sulfonate aggravates intimal hyperplasia and atherosclerosis by promoting phenotypic switching of smooth muscle cells via ERK/tPA pathway.
Bixuan Yue, Yushan Liao, Yunxiang Long, Yicheng Wang, Luoxing Xia, Mingliang Wang, Miaoyun Qiu, Chaobo Yang, Zhigao Song, Xiaowu Wang, Fengfeng Li, Zhi Zeng
Published: 202610.1016/j.jhazmat.2025.140999
Abstract
Perfluorooctane sulfonate (PFOS), a pervasive environmental contaminant, is ubiquitously detected in water, air, soil, and food chains. Emerging evidence has implicated PFOS in the pathogenesis of cardiovascular diseases, particularly atherosclerosis…
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