Journal of hazardous materialsHumansCarbon IsotopesAdipocytesEnvironmental PollutantsCell Line
13C metabolic tracing in human SGBS cells provides a potential new approach methodology for assessing metabolism-disrupting properties of environmental chemicals.
Cornelius Goerdeler, Beatrice Engelmann, Helen Broghammer, Alix Sarah Aldehoff, Martin Wabitsch, Kristin Schubert, Matthias Blüher, John T Heiker, Ulrike Rolle-Kampczyk, Martin von Bergen
Published: 202510.1016/j.jhazmat.2025.140384
Abstract
Human exposure to certain environmental chemicals, including phthalates, is linked to metabolic disruption and may thereby contribute to diseases like obesity. However, regulatory methods to evaluate such effects are lacking. DINCH was introduced as…
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