Journal of hazardous materialsOxidative StressHumansNanoparticlesPolystyrenesSorafenib
Nanoplastic-induced NAT10/ac4C axis drives both oxidative stress and chemoresistance.
Hengtao Fu, Jianfeng Sun, Zijun Shao, Caiyun Wang, Liping Bai, Guoyuan Zhu, Zhihong Jiang, Wei Zhang
Published: 202510.1016/j.jhazmat.2025.140193
Abstract
The exact molecular mechanisms of nanoplastics toxicity remain poorly understood. This study provides the first evidence that exposure to polystyrene nanoparticles (PS-NPs) induces a significant epitranscriptomic reprogramming, detecting 38 different…
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